Medical Coding Training Center in Trivandrum

                                  C88.2- Heavy Chain Disease Heavy chain diseases  are plasma cell cancers in which a clone of plasma cells produces a large quantity of pieces of abnormal antibodies called heavy chains .   Plasma cells develop from B cells ( B lymphocytes ), a type of white blood cell that normally produces   antibodies   (immunoglobulins). Antibodies are proteins that help the body fight infection. If a single   plasma cell   multiplies excessively, the resulting group of genetically identical cells (called a clone) produces a large quantity of a single type of   antibody . Because this antibody is made by a single clone, it is called a monoclonal antibody and also is known as the M-protein. People with a large quantity of the M protein often have reduced levels of other antibodies. In some cases, the antibody produced is incomplete, consisting of onl...

                           D47.22 Castleman Disease  Castleman disease Castleman disease, or Castleman syndrome , refers to a group of rare disorders involving an overgrowth of cells in the body’s lymphatic system.The lymphatic system is made up of lymph nodes (also called lymph glands) and other lymphatic tissue. This system is part of the immune system and filters harmful substances such as bacteria and viruses so they don’t spread to other parts of the body. Castleman disease can affect one or more lymph nodes in a single region of the body or it can involve multiple lymph node regions. Doctors classify the disease into different categories based on the number of lymph node regions affected.Castleman disease and its symptoms are similar to lymphomas, cancers that affect the lymph nodes.Castleman disease is rare. Doctors diagnose about 6,500-7,700 new cases in the U.S. each year. Different types of Castlem...

                      D56.0 Alpha Thalassemia Thalassemia  (thal-uh-SEE-me-uh) is an inherited blood disorder that causes your body to have less hemoglobin than normal. Hemoglobin enables red blood cells to carry oxygen. Thalassemia can cause anemia, leaving you fatigued.If you have mild thalassemia, you might not need treatment. But more severe forms might require regular blood transfusions. You can take steps to cope with fatigue, such as choosing a healthy diet and exercising regularly. Symptoms There are several types of thalassemia. The signs and symptoms you have depend on the type and severity of your condition. Thalassemia signs and symptoms can include: Fatigue Weakness Pale or yellowish skin Facial bone deformities Slow growth Abdominal swelling Dark urine Some babies show signs and symptoms of thalassemia at birth; others develop them during the first two years of life. Some people who have only one affected hemoglob...

                                                        D61.82 Mtelophythisis   Myelophthisic  anemia  is a normocytic, normochromic anemia that occurs when normal marrow space is infiltrated and replaced by nonhematopoietic or abnormal cells. Causes include tumors, granulomatous disorders, lipid storage diseases, and primary myelofibrosis. Bone marrow fibrosis often occurs as a secondary process as well. Splenomegaly may develop. Characteristic changes in peripheral blood include anisocytosis, poikilocytosis, and excessive numbers of red blood cell and white blood cell precursors. Diagnosis usually requires bone marrow biopsy. Treatment is supportive and includes measures directed at the underlying disorder. Myelofibrosis is an uncommon type of bone marrow cancer that disrupts your body's normal production of blood cells.Myelofibrosi...